understanding the relationship between psychological, neurological, hormonal and social factors, as well as their impact on body functions and overall health. This concept suggests that the physical symptoms that occur in psychosomatic diseases are not accidental or the consequence of a single organic cause, but represent the combined effects of psychological stress, repressed emotions, and mood disorders on the physiological processes of the body. These processes include the activity of the autonomic nervous system, the secretion of stress hormones such as cortisol and adrenaline, and the regulation of the immune system. These changes can weaken the body’s natural response and increase susceptibility to chronic diseases such as cardiovascular, gastrointestinal, and immune disorders. The concept also emphasizes the role of social and cultural factors in shaping psychosomatic experiences, as social relationships, family support, and the environment affect the severity of symptoms and the effectiveness of their treatment. This concept is based on a variety of models, such as the biopsychosocial model, stress and adaptation theory, and neuro-immune-hormonal interaction models, which provide a framework for understanding how psychological conditions can transform into physical symptoms and vice versa. Thus, the theoretical justification of psychosomatic disorders provides a scientific basis for understanding the causes of these conditions, predicting their development and developing comprehensive therapeutic and preventive interventions that affect both the psyche and the body, with an emphasis on the development of coping skills and psychological resilience.