a state of pathological muscle relaxation and reduced motor activity. It occurs with prolonged starvation, severe somatic and infectious diseases, poisoning, as well as with severe brain lesions of various etiologies. For example, damage to the frontal lobes of the brain (due to tumors or injuries) leads to the occurrence of the so-called apathy-adynamic syndrome – a combination of adynamia with general lethargy, lethargy.