A rare hereditary neurological disease characterized by progressive degeneration of the motor and sensory nerves (spinal amyotrophy with peripheral neuropathy), as well as brain abnormalities such as agenesis (absence) or hypoplasia (underdevelopment) of the corpus callosum.
The main symptoms include muscle weakness and atrophy, impaired sensation, problems with coordination of movements, and delayed psychomotor development. The disease is transmitted by an autosomal recessive type and usually manifests itself in childhood.