severe disorder of the nervous system, which is manifested by the predominance of signs of inhibition (coma, stopper, stunning, somnolence) – syndrome of shutdown of consciousness or excitement (twilight state, delirium, amentia, oneiroid syndrome). It occurs both in processes localized in the brain (stroke, tumor, trauma, parasitic cyst, meningitis, encephalitis), and in general infections, intoxications, endocrinopathologies, etc.