A rare genetic neurological disorder in which abnormal calcium deposits are deposited in the brain, especially in the basal ganglia, and sometimes in the cortex, thalamus, or cerebellum. Symptoms may include movement disturbances (tremor, rigidity, chorea), cognitive decline, psychiatric disorders, speech disorders, and seizures. The disease is more likely to manifest itself in middle age, but an earlier or later onset is also possible. It is transmitted mainly by the autosomal dominant type. There is no treatment that eliminates the cause; Therapy aims to control motor, cognitive, and psychiatric symptoms.