Conflict is the product of a complex interaction of the neural structures of the brain with cognitive and emotional psychological functions that regulate human behavior. Thus, from this perspective, conflict is a neuropsychological function that occurs when motivations, cognitive representations, and emotions interact disharmoniously in the brain, leading to difficulty in decision-making, hesitation, or unstable behavior. Luria also believed that psychological conflicts are not just emotional experiences; They have a biological basis that can be observed in patterns of brain activity. This paved the way for the study of the relationship between brain damage or neurological injury and conflict patterns and adjustment difficulties. The importance of this approach lies in demonstrating that conflict management requires not only adaptation to a social or psychological context, but also an understanding of the neural mechanisms that regulate it. It links the biological, cognitive, and social levels and serves as a bridge between clinical psychology and neuroscience, making it influential in areas such as neurorehabilitation and psychopathology.