The concept of basic emotions has been associated with the names of many scientists, but the most prominent scientist who laid its scientific foundation was the neuroscientist Jaak Panksepp, who was engaged in research in the field of “affective neuroscience”. He identified a group of innate, primal emotions common to humans and animals, such as fear, anger, joy, sadness, disgust, and surprise, as the brain’s “basic neuroemotional systems.” There is a profound relationship between a group of primary and basic emotions called “core emotions,” such as fear, anger, sadness, joy, and disgust, and the onset and exacerbation of psychosomatic disorders, which reflect a complex mind-body interaction. Nuclear emotions are innate responses that have evolved over time to survive and adapt to environmental and social challenges. However, when they are excessive, chronic, or unregulated, they become a stressor that affects the functions of internal organs through a variety of physiological and neurohormonal mechanisms. For example, constant fear activates the autonomic nervous system, especially the sympathetic nervous system, which leads to increased blood pressure, increased heart rate, and altered secretion of hormones such as cortisol, which weakens the immune system and increases the risk of developing ulcers or cardiovascular disease. At the same time, repressed anger may be associated with gastrointestinal diseases or an increased risk of hypertension. Deep and prolonged sadness can manifest itself in weakened immunity, susceptibility to infections, or even accelerate the course of chronic diseases. Conversely, a lack of positive emotions such as joy or love limits the ability to adapt and negatively affects the secretion of neurotransmitters – chemicals associated with well-being – such as serotonin and dopamine. Thus, nuclear emotions serve as the main centers linking internal psychological stressors with pathological physical manifestations. Therefore, understanding and managing them is crucial for the prevention and treatment of psychosomatic disorders, as they contribute to the improvement of emotional regulation, the development of awareness of emotions and the development of healthy strategies for expressing them.