methods aimed at studying the relationship between psychological, behavioral and social factors and their impact on physical health and chronic diseases. These methods include experimental studies that use observational and control models to determine the effects of psychological variables on bodily functions, such as measuring the effects of psychological stress on hormone secretion or immune system activity. They also include epidemiological and long-term studies in which groups of people are followed for many years to determine the relationship between psychological factors, such as stress and depression, and the onset or exacerbation of somatic diseases. Clinical interviews and questionnaires are used to collect psychosocial data, such as levels of anxiety and depression, as well as coping styles for stress, and compare them to biological and physiological indicators. In addition, psychosomatic research draws on modern neurophysiological measurement techniques, such as functional magnetic resonance imaging (fMRI), electroencephalography, and measurement of hormone levels and inflammatory processes in the blood and saliva, to understand the biological mechanisms linking mind and body. Methods also include using experimental animal models to study the effects of psychological factors on bodily functions and immunity, before moving on to human studies. Through these diverse techniques, researchers can build a complete picture of the mind-body interaction and develop evidence-based therapeutic and preventive interventions to promote both mental and physical health.