A theory that shows how psychological conditions can directly or indirectly affect the strength or weakness of the immune system. Studies have confirmed that chronic psychological stress, constant anxiety, and major depression can lead to impaired secretion of hormones and neurochemicals such as cortisol and adrenaline. Constantly elevated levels of these substances weaken the immune system and reduce the body’s ability to fight infections and fight disease. Emotional suppression or lack of positive coping skills increase the fragility of the immune system and contribute to the development of psychosomatic diseases. Moreover, a positive psychological state, social support and psychological stability contribute to strengthening the immune system and speeding up recovery, since the immune system functions in close relationship with the nervous and endocrine systems. Thus, the role of psychosomatics in understanding the close relationship between emotions and immunity becomes obvious. This not only explains how physical symptoms arise as a result of psychological stress, but also contributes to the development of therapeutic and preventive programs that promote immune health by improving mental health and developing healthy adaptive strategies. This clearly demonstrates that the immune system is inseparable from psychological states, but is also deeply influenced by them and constantly interacts with them.