This theory provides a conceptual and methodological framework for understanding the dynamic and complex relationships between psychological and physical factors, explaining how emotional experiences and life stressors can affect physical health both directly and indirectly. The theory of “sense of coherence” is a fundamental concept that explains individual differences in responses to stress and difficulties, explaining why some people manage to maintain good health despite exposure to severe stressors, while others develop physical symptoms or psychosomatic disorders as a result of exposure to less severe stressors. In the context of psychosomatics, this theory has become a central tool for explaining the origin of psychosomatic symptoms, as it suggests that a lack of psychological coherence, that is, a poor ability to understand and manage life situations, contributes to the occurrence of physical disorders associated with psychological stress or internal conflict. This makes the theory a link between psychiatry, health psychology and internal medicine medicine, providing a way to assess a person’s ability to cope with stress and identifying potential risks of developing psychosomatic disorders. It also underscores the importance of theory in defining therapeutic interventions, as it allows for a focus not only on treating physical symptoms, but also on strengthening the patient’s sense of integrity through medical interventions, stress management techniques, developing coping skills, and increasing life meaning. This helps to improve treatment outcomes and reduce the risk of recurrence of symptoms. In addition, the theory contributes to the understanding of the relationship between a person and his social and cultural environment, emphasizing that psychosomatic health is not just a biological state, but a product of constant interaction between the body, psyche and environment.